Abstract <em>Introduction: </em>Drinking carbohydrate-containing clear liquids until 2 hours before elective procedures improves patient satisfaction and reduces insulin resistance, but the likelihood of delayed gastric emptying, a risk factor of pulmonary aspiration in anesthesia, is unclear. Therefore, we designed a study to assess the effects of drinking carbohydrate-containing clear liquid until 2 hours before the elective gastrointestinal surgery on gastric emptying and gastric residual volume measured by ultrasonography. <em>Patients and Methods: </em>Randomized controlled trial designs including 64 patients undergoing gastrointestinal surgery in Viet Duc University Hospital. The intervention group received 400 ml maltodextrin 12.5% in 2 hours prior to surgery, and the control group fasted overnight as usual. Results: The residual fluid estimated by ultrasound in the intervention group and the intervention group were 25.70 ± 21.13 and 31.01 ± 26.74 in the controlled group (p>0.05). The gastric fluid collected by the nasogastric tube is not significantly different between the two groups (intervention group: 15.00 ± 23.34 ml; controlled group: 12.72 ± 22.43 ml). There was no aspiration case in both groups. <em>Conclusion: </em>Taking carbohydrates- containing clear liquids until 2 hours before general anesthesia influences neither gastric emptying nor perioperative complications. <em>Keywords: </em>Carbohydrate-containing clear liquids, gastric residual volume, gastric ultrasound. References <ol> <li>Goyal RK, Guo Y, Mashimo Advances in the physiology of gastric emptying. <em>Neurogastroenterol Motil</em>. 2019;31(4)</li> <li>Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective Procedures: An Updated Report by the American Society of Anesthesiologists Task Force on Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration*. <em>Anesthesiology</em>. 2017;126(3):376-393.</li> <li>Charan J, Biswas How to Calculate Sample Size for Different Study Designs in Medical Research? <em>Indian J Psychol Med. </em>2013;35(2):121-126.</li> <li>Tran S, Wolever TMS, Errett LE, Ahn H, Mazer CD, Keith M. Preoperative Carbohydrate Loading in Patients Undergoing Coronary Artery Bypass or Spinal <em>Anesth Analg</em>. 2013;117(2):305-313.</li> <li>S. Chaitra, Daïneev Palta et al. Assessment of residual gastric volume using point-of-care ultrasonography in adult patients who underwent elective surgery. <em>The Ultrasound Journal</em>. 2022; 15(7): 19- 179</li> <li>Noba L, Wakefield A. Are carbohydrate drinks more effective than preoperative fasting: A systematic review of randomized controlled trials. <em>J Clin Nurs. </em>2019;28(17-18):3096-3116.</li> <li>Mai NTN, Kien NV, Manh LD, et al. Evaluate the effects of oral maltodextrin 12.5% solution 2 hours before <em>J 108 - Clin Med Phamarcy. </em>Published online August 12, 2022.</li> <li>Ly Huyen Hoa (2019). Evaluate residual gastric volume of oral maltodextrin 12.5% solution 2 hours before <em>Resident doctor thesis defense</em>. Ho Chi Minh University of Medicine and Pharmacology.</li> <li>Gomes PC, Caporossi C, Aguilar-Nascimento JE, Silva AMC da, Araujo VMT de. Residual gastric volume evaluation with ultrasonography after ingestion of carbohydrate- or carbohydrate plus glutamine- enriched beverages: a randomized, crossover clinical trial with healthy <em>Arq Gastroenterol. </em>2017;54:33-36.</li> <li>Kaška M, Grosmanovaù T, Havel E, et The impact and safety of preoperative oral or intravenous carbohydrate administration versus fasting in colorectal surgery – a randomized controlled trial. <em>Wien Klin Wochenschr</em>. 2010;122(1):23-30.</li> <li>Yilmaz N, Çekmen N, Bilgin F, Erten E, Ozhan MO, Cosar Preoperative carbohydrate nutrition reduces postoperative nausea and vomiting compared to preoperative fasting. <em>J Res Med Sci Off J Isfahan Univ Med Sci</em>. 2013;18(10):827-832.</li> <li>Rizvanovic N, Nesek Adam V, Cauševic S, Derviševic S, Delibegovic A randomized controlled study of preoperative oral carbohydrate loading versus fasting in patients undergoing colorectal surgery. <em>Int J Colorectal Dis</em>. 2019;34(9):1551-1561</li> </ol> <!--more--> <a href="https://vjsel.com/wp-content/uploads/2024/01/BAI-4.pdf">Download file PDF</a>