<strong>Abstract</strong> <em>Introduction:</em> This study aims to evaluate the effectiveness and safety of the percutaneous biliary stent placement for malignant hilar biliary obstruction (MHBO). <em>Patients and Method:</em> Percutaneous biliary stent was placed in 50 patients with MHBO at Viet Duc University Hospital from June 2019 to July 2020. The patients were monitored during their hospitalization, at 1-month and long-term follow-up on clinical symptoms and laboratory results as well as complications. The effect and safety of this technique were evaluated. <em>Results:</em> Successful rate was 98%. The total serum bilirubin decreased from 280.06 ± 164.65 µmol/L before to 165.09±112.90 µmol/L one week later (p<0.001). Additionally, the AST and ALT significantly decreased (p<0.001). Early complication rate was 22.4%, and late complication rate was 2.0% respectively. The stent occlusion rate was 20.4%. The median survival time was 144.2 days. <em>Conclusion:</em> The percutaneous biliary stent placement is a safe and effective palliative therapy for MHBO, helps to improve liver function and quality of life of patients. <em>Keywords:</em> Biliary stent, hilar biliary obstruction, percutaneous trans-hepatic biliary stent, percutaneous trans-hepatic biliary drainage. <strong>References</strong> <ol> <li>Nakeeb A, Pitt HA, Sohn TA, Coleman J, Abrams RA, Piantadosi S, et al. <em> A spectrum of intrahepatic, perihilar, and distal tumors.</em> Ann Surg 1996; 224: 463-473.</li> <li>Corvino, Fabio et al. <em>Percutaneous "Y" biliary stent placement in palliative treatment of type 4 malignant hilar stricture.</em> Journal of gastrointestinal oncology 2016; 7(2): 255-61.</li> <li>Molnar W, Stockum AE. <em>Relief of obstructive jaundice through percutaneous transhepatic catheter--a new therapeutic method.</em> Am J Roentgenol Radium Ther Nucl Med 1974; 122(2):356-367.</li> <li>Li M, Li K, Qi X, Wu W, Zheng L, He C, et al. <em>Percutaneous transhepatic biliary stent implantation for obstructive jaundice of perihilar cholangiocarcinoma: a prospective study on predictors of stent patency and survival in 92 patients.</em> J Vasc Interv Radiol 2016 ; 27:1047-1055.</li> <li>Perdue, D. G., Freeman, M. L et al. <em>Plastic Versus Self-expanding Metallic Stents for Malignant Hilar Biliary Obstruction.</em> Journal of Clinical Gastroenterology 2008; 42(9), 1040–1046.</li> <li>Teng, F., Xian, Y.-T., Lin, J., Li, Y., & Wu, A.-L. <em>Comparison of Unilateral With Bilateral Metal Stenting for Malignant Hilar Biliary Obstruction.</em> Surg Laparosc Endosc Percutan Tech 2019; 29(1): 43-48.</li> <li>Dong Il Gwon et al. <em>Percutaneous Bilateral Metallic Stent Placement Using a Stentin-Stent Deployment Technique in Patients With Malignant Hilar Biliary Obstruction.</em> AJR 2013; 200: 909-914.</li> <li>Shiro Miyayama et al. <em>Efficacy of covered metallic stents in the treatment of unresectable malignant biliary obstruction.</em> Cardiovasc Intervent Radiol 2004; 27:349-354.</li> <li>Chung Hoang Phuong, Nguyen Dinh Luan. <em>Percutaneous biliary drainage and stent placement in patients with biliary obstruction due to advanced malignancies.</em> Journal of the Vietnam Association of Gastro-enterology. 2017;10(48):3034-3046.</li> <li>Nguyen Quoc Dung. <em>Percutaneous biliary stent for biliary obstruction.</em> Journal of Practical Medicine 2010; 727 (7): 9-12.</li> </ol> <!--more--> <a href="https://vjsel.com/wp-content/uploads/2022/05/BAI-8.pdf">Download PDF File</a>